A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate | Zendy

Lin He | Zendy; Christopher Metter | Zendy; Vitaly Margulis | Zendy; Payal Kapur | Zendy

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A Review Leveraging a Rare and Unusual Case of Basal Cell Carcinoma of the Prostate

Author(s) -

Lin He,

Christopher Metter,

Vitaly Margulis,

Payal Kapur

Publication year - 2021

Publication title -

case reports in pathology

Language(s) - English

Resource type - Journals

eISSN - 2090-6781

pISSN - 2090-679X

DOI - 10.1155/2021/5520581

Subject(s) - medicine , prostate , pathology , adenoid cystic carcinoma , adenoid , immunohistochemistry , differential diagnosis , basal cell carcinoma , basal (medicine) , myb , adenocarcinoma , carcinoma , basal cell , cancer , gene , biology , gene expression , biochemistry , insulin

Basal cell carcinoma (BCC) is a rare nonacinar variant of prostatic carcinoma. In spite of prostatic acinar adenocarcinoma being one of the most common carcinomas in prostate, <100 prostatic BCC cases have been reported to date. Adenoid cystic/cribriform histology has been described in varying proportions to occur in prostatic BCC and is reported to be associated with aggressive behavior and high risk of metastasis. Herein, we present a case of prostatic BCC with adenoid cystic morphology, comprehensively describe its immunohistochemical and MYB/MYBL1 gene rearrangement findings, discuss its differential diagnosis, and review the literature of this rare entity.

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