Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities | Zendy

Yin Li | Zendy; Zixin Sha | Zendy; Hui Peng | Zendy

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Metabolic Reprogramming in Kidney Diseases: Evidence and Therapeutic Opportunities

Author(s) -

Yin Li,

Zixin Sha,

Hui Peng

Publication year - 2021

Publication title -

international journal of nephrology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.551

H-Index - 29

eISSN - 2090-2158

pISSN - 2090-214X

DOI - 10.1155/2021/5497346

Subject(s) - reprogramming , kidney , medicine , kidney cancer , kidney disease , bioinformatics , biology , cell , biochemistry

Metabolic reprogramming originally referred to the ability of cancer cells to metabolically adapt to changes in environmental conditions to meet both energy consumption and proliferation requirements. According to recent studies, renal cells are also capable of reprogramming their metabolism after kidney injury, and these cells undergo different kinds of metabolic reprogramming in different kidney diseases. Metabolic reprogramming also plays a role in the progression and prognosis of kidney diseases. Therefore, metabolic reprogramming is not only a prominent feature but also an important contributor to the pathophysiology of kidney diseases. Here, we briefly review kidney diseases and metabolic reprogramming and discuss new ways to treat kidney diseases.

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