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Objective   To explore the optimal  b  value setting for diffusion tensor imaging of rats' spinal cord at ultrahigh field strength (7 T).Methods   Spinal cord diffusion tensor imaging data were collected from 14 rats (5 healthy, 9 spinal cord injured) with a series of  b  values (200, 300, 400, 500, 600, 700, 800, 900, and 1000 s/mm 2 ) under the condition that other scanning parameters were consistent. The image quality (including image signal-to-noise ratio and image distortion degree) and data quality (i.e., the stability and consistency of the DTI-derived parameters, referred to as data stability and data consistency) were quantitatively evaluated. The min-max normalization method was used to process the calculation results of the four indicators. Finally, the image and data quality under each  b  value were synthesized to determine the optimal  b  value.Results    b  = 200 s/mm 2  and  b  = 900 s/mm 2  ranked in the top two of the comprehensive evaluation, with the best image quality at  b  = 200 s/mm 2  and the best data quality at  b  = 900 s/mm 2 .Conclusion   Considering the shortcomings of the ability of low  b  values to reflect the microstructure,  b  = 900 s/mm 2  can be used as the optimal  b  value for 7 T spinal cord diffusion tensor scanning.

biomed research international

Effect of <math xmlns="http://www.w3.org/1998/Math/MathML" id="M1"> <mi>b</mi> </math> Value on Imaging Quality for Diffusion Tensor Imaging of the Spinal Cord at Ultrahigh Field Strength

Effect of b Value on Imaging Quality for Diffusion Tensor Imaging of the Spinal Cord at Ultrahigh Field Strength

Effect of $b$ Value on Imaging Quality for Diffusion Tensor Imaging of the Spinal Cord at Ultrahigh Field Strength