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Research on Network Model of Dentate Gyrus Based on Bionics
Author(s) -
Jin Zhang,
Xiaoping Wei,
Shiwen Zhang,
Xin Niu,
Guang Li,
Tiantian Tian
Publication year - 2021
Publication title -
journal of healthcare engineering
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.509
H-Index - 29
eISSN - 2040-2309
pISSN - 2040-2295
DOI - 10.1155/2021/4609741
Subject(s) - dentate gyrus , neuroscience , limbic lobe , bionics , computer science , hippocampus , psychology , artificial intelligence
As an important part of the brain, the dentate gyrus has an irreplaceable effect in the process of memory generation. Therefore, the study of the dentate gyrus model has important significance in the study of brain function. This paper, combined with the real anatomical structure of the dentate gyrus, is based on the existing calculation model for studying the pathological state of the dentate gyrus, a network model of dentate gyrus based on bionics. Then, a simulation experiment on the normal dentate gyrus model is performed on the NEURON platform, the output of each neuron in the model is observed, and a conclusion that the improved model can respond to stimuli, generate action potentials, and transmit them along with the neural network is made. At the same time, the output results are compared with the existing pathological models, and the characteristics of the stimulus response between neurons in the dentate gyrus under normal physiological conditions are obtained. Finally, according to the semiquantitative classification definition and quantitative classification definition of the small-world network, the model is analyzed, and it is concluded that the improved dentate gyrus network model has small-world characteristics. Therefore, the neurons in the improved dentate gyrus model are tightly connected and can simulate the real dentate gyrus to a certain extent.

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