An In Vitro Assessment of the Acid Resistance Characteristics of Nanohydroxyapatite/Silica Biocomposite Synthesized Using Mechanochemistry | Zendy

Sandile Cromwell Mkhize | Zendy; Stanley Chibuzor Onwubu | Zendy; Mbuso Mlambo | Zendy; Phumlane Selby Mdluli | Zendy

Open Access

An In Vitro Assessment of the Acid Resistance Characteristics of Nanohydroxyapatite/Silica Biocomposite Synthesized Using Mechanochemistry

Author(s) -

Sandile Cromwell Mkhize,

Stanley Chibuzor Onwubu,

Mbuso Mlambo,

Phumlane Selby Mdluli

Publication year - 2021

Publication title -

journal of nanomaterials

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.463

H-Index - 66

eISSN - 1687-4129

pISSN - 1687-4110

DOI - 10.1155/2021/4438100

Subject(s) - materials science , biocomposite , fourier transform infrared spectroscopy , mechanochemistry , mesoporous silica , surface modification , chemical engineering , composite number , composite material , nuclear chemistry , mesoporous material , nanotechnology , organic chemistry , chemistry , catalysis , engineering

This paper reports on the in vitro assessment of the acid resistance characteristics of mesoporous silica/nanohydroxyapatite (MSN@nHAp) biocomposite synthesized through the mechanochemical method. Bovine enamel models were used to study the acid resistance characteristics of the composite ( n = 5 ). X-ray diffraction and Fourier transform infrared spectroscopy were used to characterize the surface morphology of the MSN@nHAp. The XRD and FTIR results confirmed the successful syntheses and surface modification of nanohydroxyapatite with silica. The MSN@nHAp exhibits superior acid resistance characteristics. The salient aspect of this study suggests that mechanochemistry is a useful technique in the synthesis and surface modification of valuable biomaterials. The study concludes that the MSN@nHAp composite could be utilised in toothpaste formulation for oral healthcare management due to its acid resistance properties.

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