Physiology-Based Revascularization of Left Main Coronary Artery Disease | Zendy

Peter Kayaert | Zendy; Mathieu Coeman | Zendy; Sofie Gevaert | Zendy; Michel De Pauw | Zendy; Steven Haine | Zendy

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Physiology-Based Revascularization of Left Main Coronary Artery Disease

Author(s) -

Peter Kayaert,

Mathieu Coeman,

Sofie Gevaert,

Michel De Pauw,

Steven Haine

Publication year - 2021

Publication title -

journal of interventional cardiology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.764

H-Index - 51

eISSN - 1540-8183

pISSN - 0896-4327

DOI - 10.1155/2021/4218769

Subject(s) - fractional flow reserve , medicine , revascularization , cardiology , coronary artery disease , disease , clinical significance , intensive care medicine , radiology , myocardial infarction , coronary angiography

It is of critical importance to correctly assess the significance of a left main lesion. Underestimation of significance beholds the risk of inappropriate deferral of revascularization, whereas overestimation may trigger major but unnecessary interventions. This article addresses the invasive physiological assessment of left main disease and its role in deciding upon revascularization. It mainly focuses on the available evidence for fractional flow reserve and instantaneous wave-free ratio, their interpretation, and limitations. We also discuss alternative invasive physiological indices and imaging, as well as the link between physiology, ischemia, and prognosis.

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