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Since the hippocampus is of small size, low contrast, and irregular shape, a novel hippocampus segmentation method based on subspace patch-sparsity clustering in brain MRI is proposed to improve the segmentation accuracy, which requires that the representation coefficients in different subspaces should be as sparse as possible, while the representation coefficients in the same subspace should be as average as possible. By restraining the coefficient matrix with the patch-sparse constraint, the coefficient matrix contains a patch-sparse structure, which is helpful to the hippocampus segmentation. The experimental results show that our proposed method is effective in the noisy brain MRI data, which can well deal with hippocampus segmentation problem.

Hippocampus Segmentation Method Based on Subspace Patch-Sparsity Clustering in Noisy Brain MRI