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In this paper, the Trolox equivalent antioxidant capacity (TEAC) is estimated through a robust machine-learning algorithm known as the Particle Swarm Optimization-based Extreme Learning Machine (PSO-ELM) model. For this purpose, a large dataset from previously published reports was gathered. Various analyses were performed to evaluate the proposed model. The results of the statistical analysis showed that this model can predict the actual values with high accuracy, so that the calculated  R  2  and RMSE values were equal to 0.973 and 3.56, respectively. Sensitivity analysis was also performed on the effective input parameters. The leverage technique was also performed to check the accuracy of real data, and the results showed that the majority of data are reliable. This simple yet accurate model can be very powerful in predicting the Trolox equivalent antioxidant capacity values and can be a good alternative to laboratory data.

Implementing PSO-ELM Model to Approximate Trolox Equivalent Antioxidant Capacity as One of the Most Important Biological Properties of Food