Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion | Zendy

Husain Kadhem | Zendy; Kannan Sridharan | Zendy; Naser Naser | Zendy

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Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion

Author(s) -

Husain Kadhem,

Kannan Sridharan,

Naser Naser

Publication year - 2021

Publication title -

case reports in pulmonology

Language(s) - English

Resource type - Journals

eISSN - 2090-6846

pISSN - 2090-6854

DOI - 10.1155/2021/2206692

Subject(s) - tenecteplase , medicine , streptokinase , parapneumonic effusion , urokinase , tissue plasminogen activator , fibrinolytic agent , pleural effusion , fibrinolysis , surgery , intensive care medicine , thrombolysis , pleural fluid , myocardial infarction

Intrapleural thrombolytics have shown promising results in complicated parapneumonic pleural effusions reducing the need for surgical interventions. Until now, studies have evaluated primarily streptokinase, urokinase, and recently, alteplase. In this case series, we share our experience with tenecteplase—a tissue-specific plasminogen activator in 15 patients. We observed that tenecteplase is effective in 14/15 (93.3%) of our patients, and none of them had any bleeding episodes.

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