Oxidative Stress in Disease and Aging: Mechanisms and Therapies 2016 | Zendy

Claudio CabelloVerrugio | Zendy; Felipe Simón | Zendy; Capucine Trollet | Zendy; Juan F. Santibáñez | Zendy

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Oxidative Stress in Disease and Aging: Mechanisms and Therapies 2016

Author(s) -

Claudio CabelloVerrugio,

Felipe Simón,

Capucine Trollet,

Juan F. Santibáñez

Publication year - 2017

Publication title -

oxidative medicine and cellular longevity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.494

H-Index - 93

eISSN - 1942-0900

pISSN - 1942-0994

DOI - 10.1155/2017/4310469

Subject(s) - oxidative stress , reactive oxygen species , disease , diabetes mellitus , skeletal muscle , medicine , antioxidant , bioinformatics , mechanism (biology) , pulmonary disease , sarcopenia , biology , endocrinology , microbiology and biotechnology , biochemistry , philosophy , epistemology

International audienceOxidative stress (OS) is an imbalance between the formation of reactive oxygen species (ROS) and antioxidant defense mechanisms. This phenomenon increases with age and affects the normal functioning of several tissues. Furthermore, numerous chronic diseases associated with older age, such as diabetes and cardiovascular, renal, pulmonary, and skeletal muscle disorders, are also directly related to OS. Considering this relationship, the aim of many ongoing studies is to elucidate the underlying mechanisms and role of OS in disease onset and development. In particular, there is considerable emphasis on finding new therapeutic strategies for decreasing OS

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