Saccharomyces cerevisiae Catalyzed Cyclocondensation Reaction: Synthesis of Pyrazoline | Zendy

Nitesh D. Punyapreddiwar | Zendy; Atul V. Wankhade | Zendy; Sangesh P. Zodape | Zendy; Umesh R. Pratap | Zendy

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Saccharomyces cerevisiae Catalyzed Cyclocondensation Reaction: Synthesis of Pyrazoline

Author(s) -

Nitesh D. Punyapreddiwar,

Atul V. Wankhade,

Sangesh P. Zodape,

Umesh R. Pratap

Publication year - 2016

Publication title -

journal of applied chemistry

Language(s) - English

Resource type - Journals

eISSN - 2314-6923

pISSN - 2356-7171

DOI - 10.1155/2016/7425913

Subject(s) - pyrazoline , hydrazine (antidepressant) , saccharomyces cerevisiae , hydrate , catalysis , yield (engineering) , chemistry , yeast , organic chemistry , combinatorial chemistry , biochemistry , materials science , metallurgy

A simple, efficient, and environment friendly method has been developed for the synthesis of pyrazoline by the cyclocondensation of chalcones and hydrazine hydrate using very cheaper catalyst, baker’s yeast (Saccharomyces cerevisiae). The 3,5-diphenyl pyrazolines are synthesized in moderate to good yield. The method also overcomes drawbacks of the previous pyrazoline synthetic methods and provides a new efficient route to 3,5-diphenyl pyrazoline derivatives

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