Hydrogen Sulfide: Biogenesis, Physiology, and Pathology | Zendy

JinSong Bian | Zendy; Kenneth R. Olson | Zendy; Yi-Chun Zhu | Zendy

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Hydrogen Sulfide: Biogenesis, Physiology, and Pathology

Author(s) -

JinSong Bian,

Kenneth R. Olson,

Yi-Chun Zhu

Publication year - 2016

Publication title -

oxidative medicine and cellular longevity

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.494

H-Index - 93

eISSN - 1942-0900

pISSN - 1942-0994

DOI - 10.1155/2016/6549625

Subject(s) - biogenesis , hydrogen sulfide , physiology , pathology , biology , medicine , chemistry , biochemistry , sulfur , organic chemistry , gene

The seminal studies by Kimura's group in the late 1990s [1, 2] ushered in a new era of biological signaling mediated by hydrogen sulfide (H2S). H2S has been described as the third “gasotransmitter” along with nitric oxide (NO) and carbon monoxide (CO; [3]). While none of these molecules actually signal as a gas, their hydrophilicity and lipophilicity enable them to readily traverse intracellular compartments where they serve in a variety of autocrine and paracrine signals capacities.

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