Thyroid Hormones as Renal Cell Cancer Regulators | Zendy

Łukasz Szymański | Zendy; Damian Matak | Zendy; Ewa Bartnik | Zendy; Cezary Szczylik | Zendy; Anna M. Czarnecka | Zendy

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Thyroid Hormones as Renal Cell Cancer Regulators

Author(s) -

Łukasz Szymański,

Damian Matak,

Ewa Bartnik,

Cezary Szczylik,

Anna M. Czarnecka

Publication year - 2016

Publication title -

journal of signal transduction

Language(s) - English

Resource type - Journals

eISSN - 2090-1739

pISSN - 2090-1747

DOI - 10.1155/2016/1362407

Subject(s) - hormone , medicine , thyroid , thyroid hormone receptor , regulator , thyroid hormone receptor beta , renal cell carcinoma , hormone receptor , receptor , thyroid cancer , metastasis , cancer , endocrinology , cancer research , biology , gene , genetics , breast cancer

It is known that thyroid hormone is an important regulator of cancer development and metastasis. What is more, changes across the genome, as well as alternative splicing, may affect the activity of the thyroid hormone receptors. Mechanism of action of the thyroid hormone is different in every cancer; therefore in this review thyroid hormone and its receptor are presented as a regulator of renal cell carcinoma.

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