MicroRNAs: Novel Players in Cancer Diagnosis and Therapies | Zendy

Aaron L. Oom | Zendy; Brock A. Humphries | Zendy; Chengfeng Yang | Zendy

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MicroRNAs: Novel Players in Cancer Diagnosis and Therapies

Author(s) -

Aaron L. Oom,

Brock A. Humphries,

Chengfeng Yang

Publication year - 2014

Publication title -

biomed research international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.772

H-Index - 126

eISSN - 2314-6141

pISSN - 2314-6133

DOI - 10.1155/2014/959461

Subject(s) - microrna , cancer , metastasis , medicine , bioinformatics , biology , genetics , gene

First discovered in 1993, microRNAs (miRNAs) have been one of the hottest research areas over the past two decades. Oftentimes, miRNAs levels are found to be dysregulated in cancer patients. The potential use of miRNAs in cancer therapies is an emerging and promising field, with research finding miRNAs to play a role in cancer initiation, tumor growth, and metastasis. Therefore, miRNAs could become an integral part from cancer diagnosis to treatment in future. This review aims to examine current novel research work on the potential roles of miRNAs in cancer therapies, while also discussing several current challenges and needed future research.

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