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Central Arterial Hemodynamic Effects of Dark Chocolate Ingestion in Young Healthy People: A Randomized and Controlled Trial
Author(s) -
Telmo Pereira,
João Maldonado,
Mafalda Laranjeiro,
Rita Coutinho,
Ester Pinheiro de Cardoso,
Ilario Caubi Fraga de Andrade,
Jorge Conde
Publication year - 2014
Publication title -
cardiology research and practice
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.437
H-Index - 35
eISSN - 2090-8016
pISSN - 2090-0597
DOI - 10.1155/2014/945951
Subject(s) - algorithm , medicine , pulse wave velocity , mathematics , blood pressure
. The aim of this study was to assess the vascular benefits of dark chocolate in healthy and young individuals. Methods . A randomized and controlled trial was carried out involving 60 healthy volunteers, randomized into two groups: control group (CG; n = 30) and intervention group (IG; n = 30). The IG ingested a daily dosage of 10 g of dark chocolate (>75% cocoa) for a month. Blood pressure (BP), flow-mediated dilation (FMD), arterial stiffness index (ASI), aortic pulse wave velocity (PWV), and pulse wave analysis (PWA) were assessed at baseline and one week after the one-month intervention period. Results . Arterial function improved after intervention in the IG, with PWV decreasing from 6.13 ± 0.41 m/s to 5.83 ± 0.53 m/s ( P = 0.02), with no significant differences observed in the CG. A significant decrease in ASI (0.16 ± 0.01 to 0.13 ± 0.01; P < 0.001) and AiX (−15.88 ± 10.75 to −22.57 ± 11.16; P = 0.07) was also depicted for the IG. Endothelial function improved in the IG, with the FMD increasing 9.31% after the 1-month intervention ( P < 0.001), with no significant variation in the CG. Conclusion . The daily ingestion of 10 g dark chocolate (>75% cocoa) during a month significantly improves vascular function in young and healthy individuals.

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