English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Beta-lactamase producing strains of  Pseudomonas aeruginosa  are important etiological agents of hospital infections. Carbapenems are among the most effective antibiotics used against  Pseudomonas  infections, but they can be rendered infective by group B   β  -lactamase, commonly called metallo-beta lactamase. In this study, the antimicrobial sensitivity patterns of  P. aeruginosa  strains isolated from 9 different hospitals in Tehran, Iran, as well as the prevalence of MBLs genes ( bla -  VIM   and  bla -  IMP  ) were determined. A total of 212 strains of  P. aeruginosa  recovered from patients in hospitals in Tehran were confirmed by both biochemical methods and PCR. Their antimicrobial sensitivity patterns were determined by Kirby-Bauer disk diffusion method. Following MIC determination, imipenem resistant strains were selected by DDST method which was followed by PCR tests for determination of MBLs genes:  bla -  IMP   and  bla -  VIM  . The results indicated that, in the DDST phenotypic method, among the 100 imipenem resistant isolates, 75 strains were MBLs positive. The PCR test indicated that 70 strains (33%) carried  bla -  VIM   gene and 20 strains (9%) harbored  bla -  IMP  . The results indicated that the extent of antibiotic resistance among  Pseudomonas aeruginosa  is on the rise. This may be due to production of MBLs enzymes. Therefore, determination of antibiotic sensitivity patterns and MBLs production by these bacteria, can be important in control of clinical  Pseudomonas  infection.

isrn microbiology

Antibiotic Resistance Pattern and Evaluation of Metallo-Beta Lactamase Genes Includingbla-IMPandbla-VIMTypes inPseudomonas aeruginosaIsolated from Patients in Tehran Hospitals