Synthesis and Antimicrobial Activity of New Schiff Base Compounds Containing 2-Hydroxy-4-pentadecylbenzaldehyde Moiety
Author(s) -
Gadada Naganagowda,
Reinout Meijboom,
Amorn Petsom
Publication year - 2014
Publication title -
advances in chemistry
Language(s) - English
Resource type - Journals
eISSN - 2356-6612
pISSN - 2314-7571
DOI - 10.1155/2014/921857
Subject(s) - chemistry , moiety , hydrazide , schiff base , benzothiophene , acetic acid , antimicrobial , antibacterial activity , proton nmr , elemental analysis , organic chemistry , antifungal , ethanol , carbon 13 nmr , medicinal chemistry , stereochemistry , bacteria , thiophene , microbiology and biotechnology , genetics , biology
Various novel Schiff base compounds have been synthesized by reaction of 2-hydroxy-4-pentadecylbenzaldehyde with substituted benzothiophene-2-carboxylic acid hydrazide and different substituted aromatic or heterocyclic amines in the presence of acetic acid in ethanol. The structures of all these compounds were confirmed by elemental analysis, IR, 1H-NMR, 13C-NMR, and mass spectral data and have been screened for antibacterial and antifungal activity
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom