Primary Small Cell Neuroendocrine Carcinoma of Paranasal Sinuses | Zendy

Maliha Khan | Zendy; Sobia Nizami | Zendy; Erkin М Мirrakhimov | Zendy; Benjamin L. Maughan | Zendy; Justin A. Bishop | Zendy; William H. Sharfman | Zendy

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Primary Small Cell Neuroendocrine Carcinoma of Paranasal Sinuses

Author(s) -

Maliha Khan,

Sobia Nizami,

Erkin М Мirrakhimov,

Benjamin L. Maughan,

Justin A. Bishop,

William H. Sharfman

Publication year - 2014

Publication title -

case reports in medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.2

H-Index - 20

eISSN - 1687-9627

pISSN - 1687-9635

DOI - 10.1155/2014/874719

Subject(s) - medicine , paranasal sinuses , radiation therapy , prophylactic cranial irradiation , orbit (dynamics) , chemoradiotherapy , radiology , oncology , myocardial infarction , conventional pci , engineering , aerospace engineering

Small cell neuroendocrine carcinoma of the paranasal sinuses is an extremely rare and aggressive neoplasm. Despite aggressive management, the tumor carries a poor prognosis, with a high risk of local recurrence or distant metastases. The management strategy is based on that for pulmonary small cell cancer and includes platinum-based chemotherapy combined with radiotherapy. We are reporting a case of an 89-year-old female patient diagnosed with small cell carcinoma of right-sided ethmoid and sphenoid sinuses. The tumor was found to have invaded the right orbit and anterior cranial fossa. Metastases to cervical lymph nodes and bone were also found. Due to the extended stage and poor prognosis of the patient, the management plan is palliative chemoradiotherapy.

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