Targeted Delivery System of Nanobiomaterials in Anticancer Therapy: From Cells to Clinics | Zendy

SuEon Jin | Zendy; HyoEon Jin | Zendy; SoonSun Hong | Zendy

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Targeted Delivery System of Nanobiomaterials in Anticancer Therapy: From Cells to Clinics

Author(s) -

SuEon Jin,

HyoEon Jin,

SoonSun Hong

Publication year - 2014

Publication title -

biomed research international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.772

H-Index - 126

eISSN - 2314-6141

pISSN - 2314-6133

DOI - 10.1155/2014/814208

Subject(s) - nanocarriers , nanomedicine , delivery system , nanotechnology , drug delivery , cancer therapy , liposome , medicine , cancer , materials science , nanoparticle , biomedical engineering

Targeted delivery systems of nanobiomaterials are necessary to be developed for the diagnosis and treatment of cancer. Nanobiomaterials can be engineered to recognize cancer-specific receptors at the cellular levels and to deliver anticancer drugs into the diseased sites. In particular, nanobiomaterial-based nanocarriers, so-called nanoplatforms, are the design of the targeted delivery systems such as liposomes, polymeric nanoparticles/micelles, nanoconjugates, norganic materials, carbon-based nanobiomaterials, and bioinspired phage system, which are based on the nanosize of 1–100 nm in diameter. In this review, the design and the application of these nanoplatforms are discussed at the cellular levels as well as in the clinics. We believe that this review can offer recent advances in the targeted delivery systems of nanobiomaterials regarding in vitro and in vivo applications and the translation of nanobiomaterials to nanomedicine in anticancer therapy.

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