Intrauterine Growth Retardation Fetus with Trisomy 16 Mosaicism | Zendy

Takol Chareonsirisuthigul | Zendy; Suchin Worawichawong | Zendy; Rachanee Parinayok | Zendy; Patama Promsonthi | Zendy; Budsaba Rerkamnuaychoke | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Intrauterine Growth Retardation Fetus with Trisomy 16 Mosaicism

Author(s) -

Takol Chareonsirisuthigul,

Suchin Worawichawong,

Rachanee Parinayok,

Patama Promsonthi,

Budsaba Rerkamnuaychoke

Publication year - 2014

Publication title -

case reports in genetics

Language(s) - English

Resource type - Journals

eISSN - 2090-6544

pISSN - 2090-6552

DOI - 10.1155/2014/739513

Subject(s) - trisomy , fetus , umbilical cord , single umbilical artery , placenta , medicine , abnormality , karyotype , aneuploidy , obstetrics , chromosomal abnormality , growth retardation , pregnancy , anatomy , biology , chromosome , genetics , psychiatry , gene

Fetal trisomy 16 is considered uniformly lethal early in gestation. It has been reported to be associated with the variability of clinical features and outcomes. Mosaic trisomy 16 leads to a high risk of abnormality in prenatal cases. Intrauterine growth retardation (IUGR) is a common outcome of mosaic trisomy 16. Herein, we report on the case of Thai male IUGR fetus with trisomy 16 mosaicism. The fetal body was too small. Postmortem investigation of placenta revealed the abnormality including small placenta with furcated cord insertion and single umbilical cord artery. Cytogenetic study demonstrated trisomy 16 that was found 100% in placenta and only 16% in the fetal heart while other organs had normal karyotype. In addition, cardiac and other internal organs examination revealed normal morphology.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research