Open AccessThe Therapeutic Effect of Zuogui Wan in Gestational Diabetes Mellitus Rats
Author(s) -
Yuwei Wang,
Qianjin Feng,
Xin Niu,
Xinshe Liu,
Kaixia Xu,
Yang Xiang-zhu,
Huifeng Wang,
Qiuju Li
Publication year - 2014
Publication title -
journal of analytical methods in chemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.407
H-Index - 25
eISSN - 2090-8865
pISSN - 2090-8873
DOI - 10.1155/2014/737961
Subject(s) - gestational diabetes , medicine , diabetes mellitus , endocrinology , streptozotocin , gestation , pregnancy , biology , genetics
In this experiment, we established an animal model of gestational diabetes mellitus rats using streptozotocin. Using the rat model of GDM, the pregnant rats in 1-19d were divided into three groups: (1) Zuogui Wan gestational diabetes mellitus group (group I, n = 12), (2) gestational diabetes mellitus rats as the control group (group II, n = 11), and (3) rats of normal pregnancy group (group III, n = 11). Compared with gestational diabetes mellitus rats as the control group, Zuogui Wan can change the indexes of fasting blood glucose, body weight, total cholesterol, insulin, and metabolism cage index significantly in Zuogui Wan gestational diabetes mellitus group. We can conclude that Zuogui Wan has the therapeutic effect on gestational diabetes mellitus.
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