RANKL Expression in Periodontal Disease: Where Does RANKL Come from? | Zendy

Bin Chen | Zendy; Wenlei Wu | Zendy; Weibin Sun | Zendy; Qian Zhang | Zendy; Fuhua Yan | Zendy; Yin Xiao | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

RANKL Expression in Periodontal Disease: Where Does RANKL Come from?

Author(s) -

Bin Chen,

Wenlei Wu,

Weibin Sun,

Qian Zhang,

Fuhua Yan,

Yin Xiao

Publication year - 2014

Publication title -

biomed research international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.772

H-Index - 126

eISSN - 2314-6141

pISSN - 2314-6133

DOI - 10.1155/2014/731039

Subject(s) - rankl , osteoclast , bone resorption , periodontitis , resorption , dental alveolus , medicine , activator (genetics) , dentistry , receptor , chemistry

Periodontitis is an inflammatory disease characterized by periodontal pocket formation and alveolar bone resorption. Periodontal bone resorption is induced by osteoclasts and receptor activator of nuclear factor- κ B ligand (RANKL) which is an essential and central regulator of osteoclast development and osteoclast function. Therefore, RANKL plays a critical role in periodontal bone resorption. In this review, we have summarized the sources of RANKL in periodontal disease and explored which factors may regulate RANKL expression in this disease.

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research