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Eight bifidobacterial strains isolated from human breast milk have been tested for their abilities to convert linoleic acid (LA) and  α -linolenic acid (LNA) to conjugated linoleic acid (CLA) and conjugated  α -linolenic acid (CLNA), respectively. These bioactive lipids display important properties that may contribute to the maintenance and improvement human health. Three selected  Bifidobacterium breve  strains produced CLA from LA and CLNA from LNA in MRS (160–170 and 210–230  μ g mL −1 , resp.) and, also, in reconstituted skim milk (75–95 and 210–244  μ g mL −1 , resp.). These bifidobacterial strains were also able to simultaneously produce both CLA (90–105  μ g mL −1 ) and CLNA (290–320  μ g mL −1 ) in reconstituted skim milk. Globally, our findings suggest that these bifidobacterial strains are potential candidates for the design of new fermented dairy products naturally containing very high concentrations of these bioactive lipids. To our knowledge, this is the first study describing CLNA production and coproduction of CLA and CLNA by  Bifidobacterium breve  strains isolated from human milk in reconstituted skim milk.

biomed research international

Production of Conjugated Linoleic and Conjugated<i>α</i>-Linolenic Acid in a Reconstituted Skim Milk-Based Medium by Bifidobacterial Strains Isolated from Human Breast Milk

Production of Conjugated Linoleic and Conjugatedα-Linolenic Acid in a Reconstituted Skim Milk-Based Medium by Bifidobacterial Strains Isolated from Human Breast Milk