Combating Kidney Fibrosis

An estimated 10% of the world population has some form of kidney disease. Kidney fibrosis is the final common pathway of progressive kidney diseases, resulting in subsequent massive destruction of normal kidney structure and diminishing the function. Currently approved therapies are neither pathway nor cell specific in nature, due to which these therapies became ineffective in reducing the fibrosis and are associated with side effects. The understanding of the pathways and cells that are involved in the fibrosis will guide the future therapies to combat the kidney fibrosis.