Heme Consumption Reduces Hepatic Triglyceride and Fatty Acid Accumulation in a Rat Model of NAFLD Fed Westernized Diet | Zendy

Soon Yew Tang | Zendy; Irwin Kee M. Cheah | Zendy; Pei Ern Ng | Zendy; Aina Hoi | Zendy; Andrew M. Jenner | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Open Access

Heme Consumption Reduces Hepatic Triglyceride and Fatty Acid Accumulation in a Rat Model of NAFLD Fed Westernized Diet

Author(s) -

Soon Yew Tang,

Irwin Kee M. Cheah,

Pei Ern Ng,

Aina Hoi,

Andrew M. Jenner

Publication year - 2014

Publication title -

isrn oxidative medicine

Language(s) - English

Resource type - Journals

ISSN - 2314-6400

DOI - 10.1155/2014/659029

Subject(s) - medicine , hemoglobin , endocrinology , nonalcoholic fatty liver disease , triglyceride , fatty liver , cholesterol , insulin resistance , biology , chemistry , biochemistry , diabetes mellitus , disease

Studies have identified that serum-free hemoglobin subunits correlate positively with the severity of nonalcoholic fatty liver disease (NAFLD). However, the role of hemoglobin in the development of NAFLD remains unclear. In the present study, a rat model of NAFLD was developed, using a westernized diet high in saturated fat and refined sugar. Since a “westernized” diet is also high in red meat, we tested the effect of hemoglobin as a dietary source of heme in our model. Sprague-Dawley rats were fed ad libitum for 4 weeks either control diet (7% fat), westernized diet (WD, 18% fat

The content you want is available to Zendy users.

Already have an account? Click here to sign in.

Having issues? You can contact us here

Accelerating Research