Canine Filarial Infections in a HumanBrugia malayiEndemic Area of India
Author(s) -
Reghu Ravindran,
Sincy Varghese,
Suresh Nair,
Vimalkumar M. Balan,
Bindu Lakshmanan,
Riyas M. Ashruf,
Swaroop S. Kumar,
Karapparambu Gopalan Ajith Kumar,
Archana S. Nair,
Malayil Aparna,
Leena Chandrasekhar,
Sanis Juliet,
Devada Kopparambil,
Rajendran Ramachandran,
Regu Kunjupillai,
Showkath Ali M. Kakada
Publication year - 2014
Publication title -
biomed research international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 126
eISSN - 2314-6141
pISSN - 2314-6133
DOI - 10.1155/2014/630160
Subject(s) - brugia malayi , repens , dirofilaria repens , biology , staining , dirofilaria immitis , brugia pahangi , filariasis , microfilaria , dirofilariasis , pathology , helminths , immunology , botany , medicine , zoology , genetics
A very high prevalence of microfilaremia of 42.68 per cent out of 164 canine blood samples examined was observed in Cherthala (of Alappuzha district of Kerala state), a known human Brugia malayi endemic area of south India. The species of canine microfilariae were identified as Dirofilaria repens, Brugia malayi , and Acanthocheilonema reconditum . D. repens was the most commonly detected species followed by B. pahangi . D. immitis was not detected in any of the samples examined. Based on molecular techniques, microfilariae with histochemical staining pattern of “local staining at anal pore and diffuse staining at central body” was identified as D. repens in addition to those showing acid phosphatase activity only at the anal pore. Even though B. malayi like acid phosphatase activity was observed in few dogs examined, they were identified as genetically closer to B. pahangi . Hence, the possibility of dogs acting as reservoirs of human B. malayi in this area was ruled out.
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