Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents | Zendy

Ahmed A. ElSherif | Zendy; Mohamed M. Shoukry | Zendy; Abeer Taha Abd El-Karim | Zendy; Mohammad H. Barakat | Zendy

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Protonation Equilibria of Biologically Active Ligands in Mixed Aqueous Organic Solvents

Author(s) -

Ahmed A. ElSherif,

Mohamed M. Shoukry,

Abeer Taha Abd El-Karim,

Mohammad H. Barakat

Publication year - 2014

Publication title -

bioinorganic chemistry and applications

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.865

H-Index - 35

eISSN - 1565-3633

pISSN - 1687-479X

DOI - 10.1155/2014/626719

Subject(s) - protonation , chemistry , aqueous solution , proton , amino acid , biological activity , ligand (biochemistry) , combinatorial chemistry , organic chemistry , computational chemistry , receptor , ion , biochemistry , in vitro , physics , quantum mechanics

The review is mainly concerned with the protonation equilibria of biologically active ligands like amino acids, peptides, DNA constituents, and amino acid esters in nonaqueous media. Equilibrium concentrations of proton-ligand formation as a function of pH were investigated. Also, thermodynamics associated with protonation equilibria were also discussed.

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