Open AccessSynthesis and Antimicrobial Activity of Some Novel Heterocyclic Candidates via Michael Addition Involving 4-(4-Acetamidophenyl)-4-oxobut-2-enoic Acid
Author(s) -
Maher A. ElHashash,
A. ESSAWY,
Ahmed Sobhy Fawzy
Publication year - 2014
Publication title -
advances in chemistry
Language(s) - English
Resource type - Journals
eISSN - 2356-6612
pISSN - 2314-7571
DOI - 10.1155/2014/619749
Subject(s) - michael reaction , antimicrobial , nucleophile , sulfur , chemistry , organic chemistry , catalysis
This paper discusses the utility of 4-(4-acetamidophenyl)-4-oxobut-2-enoic acid as a key starting material for the preparation of a novel series of pyridazinones, thiazoles derivatives, and other heterocycles via interaction with nitrogen, sulfur, and carbon nucleophiles under Michael addition conditions and studies the antimicrobial activities of some of these compounds
Accelerating Research
Robert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom
Address
John Eccles HouseRobert Robinson Avenue,
Oxford Science Park, Oxford
OX4 4GP, United Kingdom