Water Mediated Synthesis ofN′-Arylmethylene-4,5,6,7-tetrahydro-2H-indazole-3-carbohydrazide Library | Zendy

Mahesh M. Savant | Zendy; Akshay M. Pansuriya | Zendy; Chirag V. Bhuva | Zendy; Naval Kapuriya | Zendy; Yogesh T. Naliapara | Zendy

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Water Mediated Synthesis ofN′-Arylmethylene-4,5,6,7-tetrahydro-2H-indazole-3-carbohydrazide Library

Author(s) -

Mahesh M. Savant,

Akshay M. Pansuriya,

Chirag V. Bhuva,

Naval Kapuriya,

Yogesh T. Naliapara

Publication year - 2014

Publication title -

organic chemistry international

Language(s) - English

Resource type - Journals

eISSN - 2090-2018

pISSN - 2090-200X

DOI - 10.1155/2014/567053

Subject(s) - indazole , carbohydrazide , chemistry , hydrazide , yield (engineering) , combinatorial chemistry , medicinal chemistry , organic chemistry , physics , thermodynamics

A novel two-step synthesis of 4,5,6,7-tetrahydro-2H-indazole-3-carbohydrazide has been developed. The library of N′-arylmethylene-4,5,6,7-tetrahydro-2H-indazole-3-carbohydrazide was generated by coupling of hydrazide to various aromatic and heterocyclic aldehydes in water media at ambient temperature with great flexibility regarding reaction time and yield

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