Technical Development of a New Semispherical Radiofrequency Bipolar Device (RONJA):Ex VivoandIn VivoStudies | Zendy

P Vávra | Zendy; Marek Penhaker | Zendy; Jan Grepl | Zendy; Jana Jurčíková | Zendy; Jiří Paleček | Zendy; Michal Crha | Zendy; Jaowaková | Zendy; Martin Hasal | Zendy; Martina Škrobánková | Zendy; Petr Ostruszka | Zendy; Peter Ihnát | Zendy; Patricie Delongová | Zendy; Dana Šalounová | Zendy; Nagy Habib | Zendy; P Zonča | Zendy

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Technical Development of a New Semispherical Radiofrequency Bipolar Device (RONJA):Ex VivoandIn VivoStudies

Author(s) -

P Vávra,

Marek Penhaker,

Jan Grepl,

Jana Jurčíková,

Jiří Paleček,

Michal Crha,

Jaowaková,

Martin Hasal,

Martina Škrobánková,

Petr Ostruszka,

Peter Ihnát,

Patricie Delongová,

Dana Šalounová,

Nagy Habib,

P Zonča

Publication year - 2014

Publication title -

biomed research international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.772

H-Index - 126

eISSN - 2314-6141

pISSN - 2314-6133

DOI - 10.1155/2014/532792

Subject(s) - ex vivo , ablation , biomedical engineering , radiofrequency ablation , in vivo , medicine , surgical instrument , liver tissue , thermal ablation , surgery , biology , microbiology and biotechnology

The aim of this study is to inform about the development of a new semispherical surgical instrument for the bipolar multielectrode radiofrequency liver ablation. Present tools are universal; however they have several disadvantages such as ablation of healthy tissue, numerous needle punctures, and, therefore, longer operating procedure. Our newly designed and tested semispherical surgical tool can solve some of these disadvantages. By conducting an in vivo study on a set of 12 pigs, randomly divided into two groups, we have compared efficiency of the newly developed instrument with the commonly used device. Statistical analysis showed that there were no significant differences between the groups. On average, the tested instrument RONJA had shorter ablation time in both liver lobes and reduced the total operating time. The depth of the thermal alteration was on average 4 mm larger using the newly tested instrument. The new radiofrequency method described in this study could be used in open liver surgery for the treatment of small liver malignancies (up to 2 cm) in a single application with the aim of saving healthy liver parenchyma. Further experimental studies are needed to confirm these results before clinical application of the method in the treatment of human liver malignancies.

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