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Clozapine-Induced Myocarditis: Is Mandatory Monitoring Warranted for Its Early Recognition?
Author(s) -
Tariq Munshi,
D. Volochniouk,
Tariq Hassan,
Nadia Mazhar
Publication year - 2014
Publication title -
case reports in psychiatry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.17
H-Index - 4
eISSN - 2090-682X
pISSN - 2090-6838
DOI - 10.1155/2014/513108
Subject(s) - clozapine , medicine , myocarditis , schizophrenia (object oriented programming) , antipsychotic , atypical antipsychotic , psychosis , psychiatry , intensive care medicine , pediatrics
Clozapine is an atypical antipsychotic used for treatment resistant schizophrenia. Its potential to induce agranulocytosis is well known but it can also cause myocarditis. Clozapine is the only antipsychotic known to induce this side effect, typically early in the treatment, and literature is scarce on this condition. We are presenting a case report of a 21-year-old schizophrenic male who developed myocarditis within 3 weeks of starting on clozapine for his treatment resistant psychosis. We then aim to review some of the available literature and raise awareness among physicians as this condition can potentially be fatal if not detected early.

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