Ginsenosides in Commercial Ginseng Products Analyzed by Liquid Chromatography-Tandem Mass Spectrometry | Zendy

Linda Uhr | Zendy; YuChun Chen | Zendy; Daniel Sit | Zendy; Paul C. H. Li | Zendy

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Ginsenosides in Commercial Ginseng Products Analyzed by Liquid Chromatography-Tandem Mass Spectrometry

Author(s) -

Linda Uhr,

YuChun Chen,

Daniel Sit,

Paul C. H. Li

Publication year - 2014

Publication title -

isrn analytical chemistry

Language(s) - English

Resource type - Journals

eISSN - 2090-732X

pISSN - 2090-7311

DOI - 10.1155/2014/486842

Subject(s) - ginseng , chromatography , ginsenoside , chemistry , ginsenoside rg1 , internal standard , mass spectrometry , liquid chromatography–mass spectrometry , tandem mass spectrometry , quality standard , medicine , alternative medicine , pathology

Although the LC/MS-MS method has been developed to analyze ginsenosides in ginseng roots, this method has not yet been utilized to quantify ginsenosides in ginseng products. In this paper, an internal standard method by LC/MS-MS was developed to analyze the ginsenosides content in the commercial ginseng products such as the ginseng capsules. We compare the standard addition method and the internal standard methods for the quantification of several ginsenosides (e.g., Rb1, Rb2, Rb3, Rc, Rd, Re, Rg1, and Rg3) in five commercial ginseng capsules. The results showed that the internal standard method is as good as the standard addition method and is a less tedious approach.

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