A Clinical and Pathological Overview of Vulvar Condyloma Acuminatum, Intraepithelial Neoplasia, and Squamous Cell Carcinoma
Author(s) -
Boris Léonard,
Frédéric Kridelka,
Katty Delbecque,
Frédéric Goffin,
Stéphanie Demoulin,
Jean Doyen,
Philippe Delvenne
Publication year - 2014
Publication title -
biomed research international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 126
eISSN - 2314-6141
pISSN - 2314-6133
DOI - 10.1155/2014/480573
Subject(s) - vulvar intraepithelial neoplasia , condyloma acuminatum , pathological , vulvar carcinoma , medicine , intraepithelial neoplasia , pathology , koilocyte , vulva , hpv infection , basal cell , dermatology , human papillomavirus , cervical intraepithelial neoplasia , cancer , cervical cancer , prostate
Condyloma acuminatum, intraepithelial neoplasia, and squamous cell carcinoma are three relatively frequent vulvar lesions. Condyloma acuminatum is induced by low risk genotypes of human papillomavirus (HPV). Vulvar intraepithelial neoplasia (VIN) and squamous cell carcinoma have different etiopathogenic pathways and are related or not with high risk HPV types. The goal of this paper is to review the main pathological and clinical features of these lesions. A special attention has been paid also to epidemiological data, pathological classification, and clinical implications of these diseases.
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