Molecular Phylogeny of Suid Herpesvirus 1 | Zendy

Antônio Augusto Fonseca Júnior | Zendy; Érica Bravo Sales | Zendy; Marcos Bryan Heinemann | Zendy; Jenner Karlisson Pimenta dos Reis | Zendy

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Molecular Phylogeny of Suid Herpesvirus 1

Author(s) -

Antônio Augusto Fonseca Júnior,

Érica Bravo Sales,

Marcos Bryan Heinemann,

Jenner Karlisson Pimenta dos Reis

Publication year - 2014

Publication title -

isrn virology

Language(s) - English

Resource type - Journals

ISSN - 2090-8814

DOI - 10.1155/2014/463173

Subject(s) - genbank , phylogenetic tree , pseudorabies , biology , genetics , subfamily , phylogenetics , virus , gene , evolutionary biology , virology

Pseudorabies is a disease that significantly impacts the swine industry. This disease is caused by Suid Herpesvirus 1 (SuHV-1), which is a double-stranded DNA virus that belongs to the Herpesviridae family and the Alphaherpesvirinae subfamily and exhibits a slow rate of genetic evolution. The aim of this study was to use both full and partial sequences of SuHV-1 genes available in GenBank to examine the evolution and divergence of viruses isolated in different parts of the world. Partial and complete sequences of SuHV-1 genes were obtained either from GenBank (i.e., us6, us7, us8, us9, ul14, ul49.5, and ul44) or from genetic sequencing of Brazilian SuHV-1 samples. The results of this study corroborate previous phylogenetic studies of SuHV-1 that demonstrated different evolutionary profiles of isolates from different parts of the globe, with a rapid genetic dispersion of Chinese isolates. All of the phylogenetic trees generated in this study demonstrated a large genetic distance between SuHV-1 isolates from the Western and Eastern regions of the world.

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