New Researches and Application Progress of Commonly Used Optical Molecular Imaging Technology
Author(s) -
Zhiyi Chen,
Yì Wáng,
Feng Yang,
Yan Lin,
Qiu-Lan Zhou,
Yangying Liao
Publication year - 2014
Publication title -
biomed research international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 126
eISSN - 2314-6141
pISSN - 2314-6133
DOI - 10.1155/2014/429198
Subject(s) - molecular imaging , optical imaging , drug development , computer science , medical imaging , bioluminescence imaging , nanotechnology , computational biology , medical physics , medicine , materials science , biology , artificial intelligence , drug , microbiology and biotechnology , gene , physics , optics , pharmacology , in vivo , transfection , biochemistry , luciferase
Optical molecular imaging, a new medical imaging technique, is developed based on genomics, proteomics and modern optical imaging technique, characterized by non-invasiveness, non-radiativity, high cost-effectiveness, high resolution, high sensitivity and simple operation in comparison with conventional imaging modalities. Currently, it has become one of the most widely used molecular imaging techniques and has been applied in gene expression regulation and activity detection, biological development and cytological detection, drug research and development, pathogenesis research, pharmaceutical effect evaluation and therapeutic effect evaluation, and so forth, This paper will review the latest researches and application progresses of commonly used optical molecular imaging techniques such as bioluminescence imaging and fluorescence molecular imaging.
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