Immunomodulation of Nanoparticles in Nanomedicine Applications
Author(s) -
Qing Jiao,
Liwen Li,
Qingxin Mu,
Qiu Zhang
Publication year - 2014
Publication title -
biomed research international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 126
eISSN - 2314-6141
pISSN - 2314-6133
DOI - 10.1155/2014/426028
Subject(s) - nanomedicine , immune system , nanotechnology , nanoparticle , immunosuppression , function (biology) , chemistry , medicine , materials science , biology , immunology , microbiology and biotechnology
Nanoparticles (NPs) have promising applications in medicine. Immune system is an important protective system to defend organisms from non-self matters. NPs interact with the immune system and modulate its function, leading to immunosuppression or immunostimulation. These modulating effects may bring benefits or danger. Compositions, sizes, and surface chemistry, and so forth, affect these immunomodulations. Here we give an overview of the relationship between the physicochemical properties of NPs, which are candidates to be applied in medicine, and their immunomodulation properties.
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