An Efficient, Clean, and Catalyst-Free Synthesis of Fused Pyrimidines Using Sonochemistry | Zendy

Manouchehr Mamaghani | Zendy; Khalil Tabatabaeian | Zendy; Raheleh Rezaei Araghi | Zendy; Akram Fallah | Zendy; Roghayeh Hossein Nia | Zendy

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An Efficient, Clean, and Catalyst-Free Synthesis of Fused Pyrimidines Using Sonochemistry

Author(s) -

Manouchehr Mamaghani,

Khalil Tabatabaeian,

Raheleh Rezaei Araghi,

Akram Fallah,

Roghayeh Hossein Nia

Publication year - 2014

Publication title -

organic chemistry international

Language(s) - English

Resource type - Journals

eISSN - 2090-2018

pISSN - 2090-200X

DOI - 10.1155/2014/406869

Subject(s) - chemistry , catalysis , sonochemistry , ethylene glycol , pyrimidine , solvent , quinoline , organic chemistry , combinatorial chemistry , stereochemistry

In this report, synthesis of indenopyrido[2,3-d]pyrimidine and pyrimido[4,5-b]quinoline derivatives was investigated via one-pot three-component reaction between 6-amino-2-(alkylthio)-pyrimidin-4(3H)one, 1,3-indanedione, or 1,3-cyclohexadione and arylaldehyde under ultrasonic irradiation in ethylene glycol as solvent at 65°C. In these reactions fused pyrimidine derivatives were synthesized with high to excellent yields (82–97%) and short reaction times (10–33 min)

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