New Semi-IPN Hydrogels Based on Cellulose for Biomedical Application

Cellulose pulp, obtained from a paper industry, has been dissolved in PEG/NaOH system and the resulting solution has been polymerized in the presence of monomer acrylic acid (AA) and crosslinker N,N′ methylene bisacrylamide via free radical polymerization. The Cell/PEG/poly (SA) ternary semi-IPN hydrogel, so prepared, was characterized by FTIR and TG analysis. The dynamic water uptake of various hydrogels, having different compositions, was investigated in the physiological buffer of pH 7.4 at 37°C. The various hydrogels exhibited chain-relaxation controlled swelling behavior. The uptake data was best interpreted by Schott kinetic model. The various diffusion coefficients, that is, initial (Di), average (Dave), and late time (DL), were also calculated using the dynamic water uptake data. The hydrogels showed fair pH and salt-dependent swelling behavior