Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases | Zendy

Paulo Henrique Barcellos França | Zendy; Daniel P. Barbosa | Zendy; Daniel L. da Silva | Zendy; Êurica Adélia Nogueira Ribeiro | Zendy; Antônio Euzébio Goulart Santana | Zendy; Bárbara V. O. Santos | Zendy; José Maria BarbosaFilho | Zendy; Jullyana de Souza Siqueira Quintans | Zendy; Rosana de Souza Siqueira Barreto | Zendy; Lucindo José QuintansJúnior | Zendy; João Xavier de AraújoJúnior | Zendy

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Indole Alkaloids from Marine Sources as Potential Leads against Infectious Diseases

Author(s) -

Paulo Henrique Barcellos França,

Daniel P. Barbosa,

Daniel L. da Silva,

Êurica Adélia Nogueira Ribeiro,

Antônio Euzébio Goulart Santana,

Bárbara V. O. Santos,

José Maria BarbosaFilho,

Jullyana de Souza Siqueira Quintans,

Rosana de Souza Siqueira Barreto,

Lucindo José QuintansJúnior,

João Xavier de AraújoJúnior

Publication year - 2014

Publication title -

biomed research international

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.772

H-Index - 126

eISSN - 2314-6141

pISSN - 2314-6133

DOI - 10.1155/2014/375423

Subject(s) - indole test , biology , anti infective agents , medicine , microbiology and biotechnology , antimicrobial , biochemistry

Indole alkaloids comprise a large and complex class of natural products found in a variety of marine sources. Infectious diseases remain a major threat to public health, and in the absence of long-term protective vaccines, the control of these infectious diseases is based on a small number of chemotherapeutic agents. Furthermore, the emerging resistance against these drugs makes it urgently necessary to discover and develop new, safe and, effective anti-infective agents. In this regard, the aim of this review is to highlight indole alkaloids from marine sources which have been shown to demonstrate activity against infectious diseases.

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