Cancer Stem Cells Accountability in Progression of Head and Neck Squamous Cell Carcinoma: The Most Recent Trends!
Author(s) -
Samapika Routray,
Neeta Mohanty
Publication year - 2014
Publication title -
molecular biology international
Language(s) - English
Resource type - Journals
eISSN - 2090-2190
pISSN - 2090-2182
DOI - 10.1155/2014/375325
Subject(s) - medicine , head and neck squamous cell carcinoma , cancer stem cell , head and neck , stem cell , head and neck cancer , cancer , basal cell , cancer research , squamous cell cancer , oncology , pathology , surgery , biology , genetics
Cancer stem cells (CSCs) play a major role in local recurrence and metastatic spread in head and neck squamous cell carcinomas (HNSCC). Evidence suggests that cancer stem cells are resistant to conventional therapy. So the emerging concepts of the role of cancer stem cells in the pathobiology of HNSCC should be understood carefully to be able to create new paradigms in treatment plans.
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