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Cryopreservation of Embryos and Oocytes in Human Assisted Reproduction
Author(s) -
János Konc,
Katalin Kanyó,
Rita Kriston,
Bence Somoskői,
Sándor Cseh
Publication year - 2014
Publication title -
biomed research international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 126
eISSN - 2314-6141
pISSN - 2314-6133
DOI - 10.1155/2014/307268
Subject(s) - cryopreservation , oocyte cryopreservation , embryo cryopreservation , embryo , vitrification , andrology , embryo donation , fertility preservation , embryo transfer , oocyte , human reproduction , reproduction , biology , gynecology , egg donation , fertility , medicine , microbiology and biotechnology , population , anatomy , genetics , environmental health
Both sperm and embryo cryopreservation have become routine procedures in human assisted reproduction and oocyte cryopreservation is being introduced into clinical practice and is getting more and more widely used. Embryo cryopreservation has decreased the number of fresh embryo transfers and maximized the effectiveness of the IVF cycle. The data shows that women who had transfers of fresh and frozen embryos obtained 8% additional births by using their cryopreserved embryos. Oocyte cryopreservation offers more advantages compared to embryo freezing, such as fertility preservation in women at risk of losing fertility due to oncological treatment or chronic disease, egg donation, and postponing childbirth, and eliminates religious and/or other ethical, legal, and moral concerns of embryo freezing. In this review, the basic principles, methodology, and practical experiences as well as safety and other aspects concerning slow cooling and ultrarapid cooling (vitrification) of human embryos and oocytes are summarized.

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