A Novel Potentiometric Sensor for Determination of Neurotoxinβ-N-Oxalyl-L-α,β-Diaminopropionic Acid

A novel potentiometric sensor based on ionophore (Cd(NH 2 CH 2 CH 2 OCH 2 CH 2 OCH 2 CH 2 NH 2 )Ag 3 (CN) 5 ) for the determination of β - N -oxalyl- l - α , β -diaminopropionic acid (ODAP) is developed. The ODAP-selective membrane sensor demonstrates high sensitivity and short response time. The detection limit of the ODAP-selective membrane sensor is about 2 × 10 −6  mol L -1 and the response time is shorter than 6 s. The linear dynamic range of the ODAP-selective membrane sensor is between ODAP concentrations of 1.0 × 10 −2 and 1 × 10 −6  mol L -1 . The ODAP-selective membrane sensor exhibits good operational stability for at least one week in dry conditions at 4–6°C. It has a reproducible and stable response during continuous work for at least 10 h with a relative standard deviation of 0.28% (n = 18).