Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids | Zendy

Mohammed Adnan | Zendy; Jordan Morton | Zendy; Syed Hashmi | Zendy; Sufyan Abdul Mujeeb | Zendy; William H. Kern | Zendy; Benjamin Jr. Cowley | Zendy

Open Access

Anti-GBM of Pregnancy: Acute Renal Failure Resolved after Spontaneous Abortion, Plasma Exchange, Hemodialysis, and Steroids

Author(s) -

Mohammed Adnan,

Jordan Morton,

Syed Hashmi,

Sufyan Abdul Mujeeb,

William H. Kern,

Benjamin Jr. Cowley

Publication year - 2014

Publication title -

case reports in nephrology

Language(s) - English

Resource type - Journals

eISSN - 2090-6641

pISSN - 2090-665X

DOI - 10.1155/2014/243746

Subject(s) - medicine , hemodialysis , abortion , pregnancy , dialysis , cyclophosphamide , disease , renal function , acute kidney injury , obstetrics , surgery , chemotherapy , genetics , biology

Antiglomerular basement membrane disease presenting during pregnancy is very uncommon. We present a case of a pregnant female who presented with acute renal failure needing dialysis from Goodpasture's disease. She responded very well to just plasma exchange, high dose steroids, and hemodialysis. Cyclophosphamide was never started on this patient. She had a spontaneous abortion in her 8th week of pregnancy and henceforth did very well to regain her renal function. Patient became hemodialysis independent at 2 months and returned to her baseline kidney function at 6 months. We present this remarkable case of recovery from acute renal failure in a patient with anti-GBM disease. We think the flare-up of renal failure was pregnancy related which resolved after spontaneous abortion.

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