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Differential, difference, and dynamic equations are used for modeling many problems arising in the engineering and natural sciences. Therefore, analysis of qualitative properties of solutions to such equations is crucial for applications. It is important to develop new theories and methods, as well as to modify and refine thewell-known techniques, for the analysis of new classes of problems. We received 11 papers for possible publication. Five papers published in this special issue address a number of challenging problems. The special issue opens with the contribution by Professor R. P. Silva who gives the characterization of the limiting behavior of solutions of elliptic equations driven by the p-Laplacian operator with Neumann boundary conditions posed in a family of thin domains. Professors Z. Luo et al. consider a class of generalized nspecies Lotka-Volterra type and Gilpin-Ayala type competition systems with multiple delays and impulses. Using Krasnoselskii fixed point theorem in a cone of Banach space, they derive some verifiable necessary and sufficient conditions for the existence of positive periodic solutions of the previously mentioned. As applications, some special cases of the previous system are examined and some earlier results are extended and improved. Professors M. Unal and Y. N. Raffoul use the fixed point theory to investigate the qualitative analysis of a nonlinear delay dynamic equation on an arbitrary time scale.They illustrate new results by applying them to various kinds of time scales. In the paper by Professor A. Reinfelds, the conjugacy of a discrete semidynamical system and its partially decoupled discrete semidynamical system in a Banach space is proved in a neighbourhood of the nontrivial invariant manifold. The contribution by Professors S. H. Da Silva et al. closes this special issue. They show normal hyperbolicity property of curves of equilibria andprove the continuity of global attractors for the flow of a class of nonlocal evolution equations with respect to some functional parameter. We hope that this collection of papers will attract interest of researchers working in related areas and will stimulate further progress in the Qualitative Theory of Differential, Difference, and Dynamic Equations.