Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal Cancer | Zendy

JiHoon Choi | Zendy; Jung Ar Shin | Zendy; Hye Kyeong Park | Zendy; Su Young Kim | Zendy; Hoon Jung | Zendy; Sung-Soon Lee | Zendy; Hyeran Lee | Zendy; HyeonKyoung Koo | Zendy

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Sarcoidosis Associated with Oxaliplatin-Based Chemotherapy for Colorectal Cancer

Author(s) -

JiHoon Choi,

Jung Ar Shin,

Hye Kyeong Park,

Su Young Kim,

Hoon Jung,

Sung-Soon Lee,

Hyeran Lee,

HyeonKyoung Koo

Publication year - 2014

Publication title -

case reports in oncological medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.173

H-Index - 7

eISSN - 2090-6714

pISSN - 2090-6706

DOI - 10.1155/2014/203027

Subject(s) - oxaliplatin , folinic acid , medicine , folfox , colorectal cancer , sarcoidosis , chemotherapy , oncology , lung cancer , gastroenterology , cancer

Acute lung injury occasionally occurs after chemotherapy, but pulmonary toxicities by oxaliplatin-based chemotherapy have rarely been identified. A 76-year-old female with rectosigmoid colon cancer presented with ongoing dyspnea after the eighth cycle of standard chemotherapy (5-fluorouracil, sodium folinic acid, and oxaliplatin: FOLFOX). Nodular consolidation progressed despite antibiotics and BAL fluid analysis was compatible with the diagnosis of sarcoidosis. Corticosteroid therapy rapidly improved the symptoms and radiographic findings. We report this first case of secondary sarcoidosis related to FOLFOX therapy with review of references.

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