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Comparative Study on the Synergistic Action of Differentially Synthesized Silver Nanoparticles with β-Cephem Antibiotics and Chloramphenicol
Author(s) -
Neethu Hari,
Tincy K. Thomas,
A. Jayakumaran Nair
Publication year - 2014
Publication title -
journal of nanoscience
Language(s) - English
Resource type - Journals
eISSN - 2356-749X
pISSN - 2314-6931
DOI - 10.1155/2014/201482
Subject(s) - cephem , antibiotics , chloramphenicol , silver nanoparticle , chemistry , nanoparticle , antibacterial activity , nuclear chemistry , microbiology and biotechnology , antimicrobial , combinatorial chemistry , bacteria , nanotechnology , biochemistry , materials science , organic chemistry , biology , carboxylic acid , genetics
Synergistic activity of cephem antibiotics with silver nanoparticles (Ag NPs) was investigated. Silver nanoparticles were synthesized through biological and chemical method. The combined action of β-lactam cephem antibiotics with both green and chemically synthesized silver nanoparticles enhances the antibacterial activity against wide range of antibiotic resistant pathogens and making them applicable to medical devices and microbial control systems. Synergistic activity of chloramphenicol with silver nanoparticles was also studied

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