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Homocysteine Serum Levels in Diabetic Patients with Non Proliferative, Proliferative and without Retinopathy
Author(s) -
Giulia Malaguarnera,
Caterina Gagliano,
Maria Giordano,
Salvatore Salomone,
Marco Vacante,
Claudio Bucolo,
Filippo Caraci,
Michele Reibaldi,
Filippo Drago,
Teresio Avitabile,
Massimo Motta
Publication year - 2014
Publication title -
biomed research international
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.772
H-Index - 126
eISSN - 2314-6141
pISSN - 2314-6133
DOI - 10.1155/2014/191497
Subject(s) - diabetic retinopathy , homocysteine , medicine , plasma homocysteine , diabetes mellitus , retinopathy , complication , type 2 diabetes mellitus , endocrinology , ophthalmology , gastroenterology
Homocysteine has been associated with extracellular matrix changes. The diabetic retinopathy is a neurovascular complication of diabetes mellitus and it is the leading cause of vision loss among working adults worldwide. In this study, we evaluate the role of homocysteine in diabetic retinopathy analyzing the plasma levels of homocysteine in 63 diabetic type 2 patients with nonproliferative retinopathy (NPDR), 62 patients with proliferative diabetic retinopathy (PDR), 50 healthy subjects used as control group, and 75 randomly selected patients.

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