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Antimicrobial Studies of N-Heterocyclic Carbene Silver Complexes Containing Benzimidazol-2-ylidene Ligand
Author(s) -
Yetkın Gök,
Yakup Sarı,
Senem Akkoç,
İlknur Özdemır,
Selamı Günal
Publication year - 2014
Publication title -
international journal of inorganic chemistry
Language(s) - English
Resource type - Journals
eISSN - 2090-2026
pISSN - 2090-2034
DOI - 10.1155/2014/191054
Subject(s) - carbene , antimicrobial , candida albicans , pseudomonas aeruginosa , chemistry , candida tropicalis , enterococcus faecalis , dichloromethane , escherichia coli , microbiology and biotechnology , staphylococcus aureus , ligand (biochemistry) , agar dilution , agar , corpus albicans , silver nitrate , bacteria , nuclear chemistry , organic chemistry , biology , minimum inhibitory concentration , catalysis , biochemistry , genetics , receptor , solvent , gene
Seven novel 4-vinylbenzyl substituted N-heterocyclic carbene (NHC) silver complexes were synthesized from different benzimidazolium salts and silver (I) oxide in dichloromethane at room temperature. These new 4-vinylbenzyl substituted NHC silver complexes were characterized by spectroscopic (NMR, IR) and elemental analysis techniques. Using the agar dilution procedure, the antimicrobial activities of these synthesized new compounds were investigated against Gram (+)/(−) bacterial and fungal strains. These NHC silver complexes showed effective activities against Escherichia coli, Pseudomonas aeruginosa (Gram-negative bacterial strains), Enterococcus faecalis, Staphylococcus aureus (Gram-positive bacterial strains), and Candida tropicalis and Candida albicans (fungal strains)

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