Severe Acute Radiation Dermatitis in a Patient with Argyria | Zendy

Peter Gorayski | Zendy; Mark B. Pinkham | Zendy; James Muir | Zendy; Andrew Pullar | Zendy

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Severe Acute Radiation Dermatitis in a Patient with Argyria

Author(s) -

Peter Gorayski,

Mark B. Pinkham,

James Muir,

Andrew Pullar

Publication year - 2014

Publication title -

case reports in oncological medicine

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 0.173

H-Index - 7

eISSN - 2090-6714

pISSN - 2090-6706

DOI - 10.1155/2014/154349

Subject(s) - medicine , dermatology , radiation therapy , basal cell , chemoradiotherapy , merkel cell carcinoma , surgery , carcinoma

Argyria is a rare cutaneous condition due to dermal silver deposition leading to irreversible blue-grey discoloration. Acute radiation dermatitis (RD) is an expected toxicity in patients undergoing radiotherapy but it is unknown to what extent argyria affects the onset and severity of RD. We report a patient with argyria treated with concurrent chemoradiotherapy for Merkel cell carcinoma who experienced an unexpectedly brisk and severe RD during treatment. Possible mechanisms for this interaction are considered.

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