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. Gastrointestinal stromal tumors of the esophagus are rare.  Case Presentation . This is a case of a 50-year-old male patient who was referred to our department complaining of atypical chest pain. A chest computed tomographic scan and endoscopic ultrasound revealed a submucosal esophageal tumor measuring 5 cm in its largest diameter. Suspecting a leiomyoma, we performed enucleation via right thoracotomy. The pathology report yielded a diagnosis of an esophageal gastrointestinal stromal tumor. The patient has shown no evidence of recurrence one year postoperatively.  Conclusions . This report illustrates the complexity and dilemmas inherent in diagnosing and treating esophageal GISTs.

Esophageal Gastrointestinal Stromal Tumor: Diagnostic Complexity and Management Pitfalls